Acetonitrile

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CAS Number: 75-05-8

Acetonitrile (CAS 75-05-8) is a chemical tracked by the EPA Toxics Release Inventory (TRI) program under Section 313 of the Emergency Planning and Community Right-to-Know Act. The TRI requires industrial facilities above specified threshold quantities to disclose annual manufacturing, processing, and otherwise-used volumes, along with quantities released to air, water, land, and off-site transfers.

Across the United States, 181 facilities have filed TRI Form R disclosures for Acetonitrile, with a cumulative reported release volume of 84.9M lbs. The chemical is not flagged as a carcinogen in the TRI classification set. The largest individual disclosure in the current dataset comes from INEOS NITRILES USA LLC GREEN LAKE PLANT in TX at 33.9M lbs.

TRI volumes are self-reported estimates, not measured stack emissions, and each pound counts equally regardless of chemical toxicity, so total pounds should not be equated with total risk. Inclusion of a chemical or facility in the TRI does not itself establish a health hazard; it documents the public right-to-know record. Consult EPA's IRIS (Integrated Risk Information System) and the Agency for Toxic Substances and Disease Registry for health-effect summaries.

Release Summary

Total Releases
84.9M lbs
Number of Facilities
181
Carcinogen
No
Persistent Bioaccumulative Toxicant
No

Which facilities release the most of this chemical?

Facilities with the largest reported releases of Acetonitrile. Up to 50 shown.

# Facility Release (lbs)
1 Ineos Nitriles USA LLC Green Lake Plant 33.9M lbs
2 Cornerstone Chemical Co LLC 27.2M lbs
3 Ineos Nitriles USA LLC 15.0M lbs
4 Basin Electric Antelope Valley Station 1.6M lbs
5 Ascend Performance Materials-Chocolate Bayou Plant 1.6M lbs
6 Ambiopharm Inc. 1.3M lbs
7 Covoro Mining Solutions LLC 858.6K lbs
8 Lyondell Chemical Co 371.4K lbs
9 Cepheid - Bothell 213.3K lbs
10 Inv Nylon Chemicals Americas Orange Site 177.8K lbs
11 Emd Millipore Corp 176.0K lbs
12 Novo Nordisk Pharmaceutical Industries LP 155.7K lbs
13 Integrated Dna Technologies 134.2K lbs
14 Nova Molecular Sumter LLC 119.9K lbs
15 Emerald Performance Materials LLC 119.4K lbs
16 Viatris Pharmaceuticals LLC 104.6K lbs
17 Inv Nylon Chemicals Americas Victoria Site 91.1K lbs
18 Eurofins Mwg Operon LLC 67.5K lbs
19 Fmc Corp - Mobile Manufacturing Center 67.2K lbs
20 Corteva Agriscience LLC - Midland 63.4K lbs
21 Veolia Es Technical Solutions L.L.C. 63.2K lbs
22 Chemgenes Corp 55.1K lbs
23 Exxonmobil Baton Rouge Chemical Plant (part) 53.4K lbs
24 Lilly Technology Center 47.8K lbs
25 Berg Lacquer Co 44.5K lbs
26 Phenomenex Inc 39.8K lbs
27 Corden Pharma Colorado Inc 39.2K lbs
28 Gentex Corp Automotive Div 39.1K lbs
29 Tm Deer Park Services LP 34.1K lbs
30 Lilly del Caribe Inc Carolin A 31.3K lbs
31 Evonik Corp Tippecanoe Laboratories 29.6K lbs
32 Ineos USA LLC - Chocolate Bayou Plant 27.9K lbs
33 Fmc Agricultural Caribe Industries Ltd 27.0K lbs
34 Goodyear Tire & Rubber Co 23.3K lbs
35 Shell Chemical LP 22.6K lbs
36 W.r. Grace & Co. 22.5K lbs
37 Agilent Technologies Inc 19.8K lbs
38 Integrated Dna Technologies 19.4K lbs
39 Integrated Dna Technologies 18.4K lbs
40 Celanese Acetate LLC - Celco Plant 16.7K lbs
41 Tedia Co LLC 15.3K lbs
42 Nitto Denko Avecia Inc. 15.2K lbs
43 Emerald Services Inc 13.7K lbs
44 Lgc Biosearch Technologies Inc 12.6K lbs
45 1500 South Tibbs LLC 12.2K lbs
46 Buzzi Unicem Usa-Cape Girardeau 11.2K lbs
47 The Dow Chemical Co 11.2K lbs
48 Eastman Kodak Co Eastman Business Park 10.8K lbs
49 W R Grace & Co 10.4K lbs
50 Vwr Chemicals LLC 9.6K lbs

Frequently Asked Questions

What is Acetonitrile?
Acetonitrile (CAS Number: 75-05-8) is a chemical tracked by the EPA Toxic Release Inventory (TRI) program. 181 facilities in the United States report releasing this chemical to the EPA.
How much Acetonitrile is released in the U.S.?
U.S. facilities have reported a total of 84.9M lbs of Acetonitrile releases to the EPA Toxic Release Inventory across 181 facilities. Release quantities are self-reported estimates. This includes releases to air, water, land, and off-site transfers.
Is Acetonitrile harmful to health?
Acetonitrile is not classified as a carcinogen in the EPA TRI database. Health effects depend on exposure levels, duration, and route. For specific health questions, consult a toxicologist or your local health agency.
Which facilities release the most Acetonitrile?
The largest reported releasers of Acetonitrile include facilities across multiple states. Release data is self-reported annually to the EPA under the TRI program. View the full list of 181 facilities on this page.
What is the CAS number for Acetonitrile?
The CAS (Chemical Abstracts Service) Registry Number for Acetonitrile is 75-05-8. CAS numbers are unique numerical identifiers assigned to every chemical substance described in the open scientific literature. This identifier is used to search scientific databases and regulatory filings.

Health Information

Data comes from the EPA Toxic Release Inventory (TRI) program. Release quantities are self-reported by facilities and may represent estimates. The total shown aggregates reports across all facilities and reporting years.

PlainEnviro presents this data without advocacy framing. The presence of a chemical in the TRI database does not by itself indicate a health risk at current exposure levels. For health-related questions about specific chemical exposures, consult your local health agency or a toxicologist.

Related

Data sourced from the U.S. Environmental Protection Agency (EPA). See our methodology for details. Retrieved and formatted by PlainEnviro Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from the EPA Toxic Release Inventory (TRI). Consult a qualified professional before making decisions based on this data.