Chlorodifluoromethane (hcfc-22)

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CAS Number: 75-45-6

Chlorodifluoromethane (hcfc-22) (CAS 75-45-6) is a chemical tracked by the EPA Toxics Release Inventory (TRI) program under Section 313 of the Emergency Planning and Community Right-to-Know Act. The TRI requires industrial facilities above specified threshold quantities to disclose annual manufacturing, processing, and otherwise-used volumes, along with quantities released to air, water, land, and off-site transfers.

Across the United States, 72 facilities have filed TRI Form R disclosures for Chlorodifluoromethane (hcfc-22), with a cumulative reported release volume of 5.5M lbs. The chemical is not flagged as a carcinogen in the TRI classification set. The largest individual disclosure in the current dataset comes from CHEMOURS LOUISVILLE PLANT in KY at 2.4M lbs.

TRI volumes are self-reported estimates, not measured stack emissions, and each pound counts equally regardless of chemical toxicity, so total pounds should not be equated with total risk. Inclusion of a chemical or facility in the TRI does not itself establish a health hazard; it documents the public right-to-know record. Consult EPA's IRIS (Integrated Risk Information System) and the Agency for Toxic Substances and Disease Registry for health-effect summaries.

Release Summary

Total Releases
5.5M lbs
Number of Facilities
72
Carcinogen
No
Persistent Bioaccumulative Toxicant
No

Which facilities release the most of this chemical?

Facilities with the largest reported releases of Chlorodifluoromethane (hcfc-22). Up to 50 shown.

# Facility Release (lbs)
1 Chemours Louisville Plant 2.4M lbs
2 Mda Manufacturing Inc 574.9K lbs
3 Daikin America Inc 466.7K lbs
4 Westlake Chemicals & Vinyls LLC 246.0K lbs
5 National Refrigerants Inc. 228.6K lbs
6 Louisville Packaging 140.5K lbs
7 Chemours Washington Works 112.0K lbs
8 Lennox Aes-Tallassee 87.0K lbs
9 Hudson Technologies Co 73.9K lbs
10 Aes Industries Inc 73.2K lbs
11 A-Gas US Inc 65.8K lbs
12 Lennox Aes-Weatherford 64.9K lbs
13 Basf Corp 59.9K lbs
14 Olin Corp 56.6K lbs
15 Eastman Chemical Co Tennessee Operations 53.2K lbs
16 The Dow Chemical Co - Louisiana Operations 50.6K lbs
17 Brainerd Chemical Midwest LLC 48.8K lbs
18 Tronox LLC 43.1K lbs
19 Kraft Heinz Foods Co 42.0K lbs
20 Louisiana Pigment Co LP 41.0K lbs
21 Westlake US 2 LLC 39.0K lbs
22 Blue Cube Operations LLC - Plaquemine Site 38.5K lbs
23 Martinez Refining Co LLC 33.0K lbs
24 Arkema Inc 28.6K lbs
25 Hemlock Semiconductor Operations LLC 27.7K lbs
26 Ineos Styrolution America LLC 26.6K lbs
27 Lennox Aes-Reno 25.5K lbs
28 Sabic Innovative Plastics Mt. Vernon LLC 24.6K lbs
29 Freeport_olin Bc 23.2K lbs
30 Sabic Innovative Plastics US LLC 21.1K lbs
31 Hudson Technologies Co 17.9K lbs
32 Hudson Technologies Co 17.1K lbs
33 Albemarle Corp South Plant 16.3K lbs
34 Mexichem Fluor Inc 15.9K lbs
35 Occidental Chemical Corp 15.9K lbs
36 A-Gas US Inc 14.2K lbs
37 Conagra Foods - Sylvester 14.0K lbs
38 Gb Biosciences LLC 13.2K lbs
39 Dupont Circleville Plant 12.4K lbs
40 A-Gas US Inc 11.8K lbs
41 Smithfield Foods 11.6K lbs
42 Exxonmobil Refining & Supply Baytown Refinery (part) 11.2K lbs
43 Primester Gp 11.0K lbs
44 Evonik Corp 10.7K lbs
45 Corteva Agriscience LLC 10.6K lbs
46 Grifols Therapeutics LLC 10.0K lbs
47 Exxonmobil Baytown Chemical Plant (part) 9.9K lbs
48 Summit Refrigerants 6.9K lbs
49 Baxter Healthcare of Puerto Rico LLC 4.5K lbs
50 Appvion LLC 4.1K lbs

Frequently Asked Questions

What is Chlorodifluoromethane (hcfc-22)?
Chlorodifluoromethane (hcfc-22) (CAS Number: 75-45-6) is a chemical tracked by the EPA Toxic Release Inventory (TRI) program. 72 facilities in the United States report releasing this chemical to the EPA.
How much Chlorodifluoromethane (hcfc-22) is released in the U.S.?
U.S. facilities have reported a total of 5.5M lbs of Chlorodifluoromethane (hcfc-22) releases to the EPA Toxic Release Inventory across 72 facilities. Release quantities are self-reported estimates. This includes releases to air, water, land, and off-site transfers.
Is Chlorodifluoromethane (hcfc-22) harmful to health?
Chlorodifluoromethane (hcfc-22) is not classified as a carcinogen in the EPA TRI database. Health effects depend on exposure levels, duration, and route. For specific health questions, consult a toxicologist or your local health agency.
Which facilities release the most Chlorodifluoromethane (hcfc-22)?
The largest reported releasers of Chlorodifluoromethane (hcfc-22) include facilities across multiple states. Release data is self-reported annually to the EPA under the TRI program. View the full list of 72 facilities on this page.
What is the CAS number for Chlorodifluoromethane (hcfc-22)?
The CAS (Chemical Abstracts Service) Registry Number for Chlorodifluoromethane (hcfc-22) is 75-45-6. CAS numbers are unique numerical identifiers assigned to every chemical substance described in the open scientific literature. This identifier is used to search scientific databases and regulatory filings.

Health Information

Data comes from the EPA Toxic Release Inventory (TRI) program. Release quantities are self-reported by facilities and may represent estimates. The total shown aggregates reports across all facilities and reporting years.

PlainEnviro presents this data without advocacy framing. The presence of a chemical in the TRI database does not by itself indicate a health risk at current exposure levels. For health-related questions about specific chemical exposures, consult your local health agency or a toxicologist.

Related

Data sourced from the U.S. Environmental Protection Agency (EPA). See our methodology for details. Retrieved and formatted by PlainEnviro Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from the EPA Toxic Release Inventory (TRI). Consult a qualified professional before making decisions based on this data.