EPA TRI Chemical

Chlorodifluoromethane (hcfc-22)

CAS Number: 75-45-6

Total releases
5.5M lbs
Number of facilities
72
Carcinogen
No
PBT substance
No
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According to the EPA Toxics Release Inventory, Chlorodifluoromethane (hcfc-22) (CAS 75-45-6) is disclosed by 72 Form R facilities totaling 5.5M lbs of reported releases. TRI pounds are self-reported disclosure totals, not a measured public-health risk score.

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Chlorodifluoromethane (hcfc-22) (CAS 75-45-6) is a chemical tracked by the EPA Toxics Release Inventory (TRI) program under Section 313 of the Emergency Planning and Community Right-to-Know Act. The TRI requires industrial facilities above specified threshold quantities to disclose annual manufacturing, processing, and otherwise-used volumes, along with quantities released to air, water, land, and off-site transfers.

A carcinogen flag, when present on other chemicals in this database, reflects an assessment from EPA, IARC, or the National Toxicology Program rather than a TRI-specific determination. The largest individual disclosure in the current dataset comes from CHEMOURS LOUISVILLE PLANT in KY at 2.4M lbs.

TRI volumes are self-reported estimates, not measured stack emissions, and each pound counts equally regardless of chemical toxicity, so total pounds should not be equated with total risk. Inclusion of a chemical or facility in the TRI does not itself establish a health hazard; it documents the public right-to-know record. Consult EPA's IRIS (Integrated Risk Information System) and the Agency for Toxic Substances and Disease Registry for health-effect summaries.

AIR pathway mix

Chlorodifluoromethane (hcfc-22): how the 5.5M lbs splits

5.5M lbs across all reported pathways

  • Air Releases5.2M lbs95.4%
  • Off-site Transfers250.7K lbs4.6%

Chlorodifluoromethane (hcfc-22)'s 5.5M lbs Form-R total is AIR, with air releases making up 95.4% of the bar. Next segment: off-site transfers at 4.6%.

Trend & Where It's Reported

Reported Release Trend

Between 2019 and 2023, cumulative annual Chlorodifluoromethane (hcfc-22) releases across all reporting facilities decreased by 32% (1.5M lbs → 1.0M lbs). Year-to-year swings reflect facility openings/closures and reporting changes as much as underlying activity.

Geographic Concentration

Reporting for Chlorodifluoromethane (hcfc-22) is concentrated: Kentucky accounts for 47.1% of the reported total (3 facilities). Next: Alabama.

  • Kentucky 2.6M lbs
  • Alabama 1.2M lbs
  • Louisiana 491.1K lbs
  • New Jersey 229.0K lbs
  • Texas 213.5K lbs
Industry Sources

Reporting for Chlorodifluoromethane (hcfc-22) is highly concentrated by industry: Chemicals facilities account for 86.6% of the reported total (46 facilities). Next: Chemical Wholesalers.

  • Chemicals 4.7M lbs
  • Chemical Wholesalers 295.3K lbs
  • Fabricated Metals 250.7K lbs
  • Food 67.6K lbs
  • Petroleum 44.2K lbs

Which facilities release the most of this chemical?

Facilities with the largest reported releases of Chlorodifluoromethane (hcfc-22). Up to 50 shown.

# Facility Release (lbs)
1 Chemours Louisville Plant
2.4M lbs
2 Mda Manufacturing Inc
574.9K lbs
3 Daikin America Inc
466.7K lbs
4 Westlake Chemicals & Vinyls LLC
246.0K lbs
5 National Refrigerants Inc.
241.6K lbs
6 Louisville Packaging
140.5K lbs
7 Chemours Washington Works
112.0K lbs
8 Lennox Aes-Tallassee
87.0K lbs
9 Hudson Technologies Co
73.9K lbs
10 Aes Industries Inc
73.2K lbs
11 A-Gas US Inc
65.8K lbs
12 Lennox Aes-Weatherford
64.9K lbs
13 Basf Corp
59.9K lbs
14 Olin Corp
56.6K lbs
15 Eastman Chemical Co Tennessee Operations
53.2K lbs
16 The Dow Chemical Co - Louisiana Operations
50.6K lbs
17 Brainerd Chemical Midwest LLC
48.8K lbs
18 Tronox LLC
43.1K lbs
19 Kraft Heinz Foods Co
42.0K lbs
20 Louisiana Pigment Co LP
41.0K lbs
21 Westlake US 2 LLC
39.0K lbs
22 Blue Cube Operations LLC - Plaquemine Site
38.5K lbs
23 Martinez Refining Co LLC
33.0K lbs
24 Arkema Inc
28.6K lbs
25 Hemlock Semiconductor Operations LLC
27.7K lbs
26 Ineos Styrolution America LLC
26.6K lbs
27 Lennox Aes-Reno
25.5K lbs
28 Sabic Innovative Plastics Mt. Vernon LLC
24.6K lbs
29 Freeport_olin Bc
23.2K lbs
30 Sabic Innovative Plastics US LLC
21.1K lbs
31 Hudson Technologies Co
17.9K lbs
32 Hudson Technologies Co
17.1K lbs
33 Albemarle Corp South Plant
16.3K lbs
34 Mexichem Fluor Inc
15.9K lbs
35 Occidental Chemical Corp
15.9K lbs
36 A-Gas US Inc
14.2K lbs
37 Conagra Foods - Sylvester
14.0K lbs
38 Gb Biosciences LLC
13.2K lbs
39 Dupont Circleville Plant
12.4K lbs
40 A-Gas US Inc
11.8K lbs
41 Smithfield Foods
11.6K lbs
42 Exxonmobil Refining & Supply Baytown Refinery (part)
11.2K lbs
43 Primester Gp
11.0K lbs
44 Evonik Corp
10.7K lbs
45 Corteva Agriscience LLC
10.6K lbs
46 Grifols Therapeutics LLC
10.0K lbs
47 Exxonmobil Baytown Chemical Plant (part)
9.9K lbs
48 Summit Refrigerants
6.9K lbs
49 Baxter Healthcare of Puerto Rico LLC
5.3K lbs
50 Appvion LLC
4.1K lbs

Frequently Asked Questions

What is Chlorodifluoromethane (hcfc-22) in the EPA TRI?
Chlorodifluoromethane (hcfc-22) (CAS Number: 75-45-6) is a chemical tracked by the EPA Toxic Release Inventory (TRI) program. It is not marked as a carcinogen in the TRI classification set. 72 facilities in the United States report releasing this chemical to the EPA.
How much Chlorodifluoromethane (hcfc-22) is disclosed in U.S. TRI filings?
U.S. facilities have reported a total of 5.5M lbs of Chlorodifluoromethane (hcfc-22) releases to the EPA Toxic Release Inventory across 72 facilities. Release quantities are self-reported estimates covering air, water, land, and off-site transfers. They are disclosure totals, not toxicity-weighted harm scores.
How does EPA TRI classify Chlorodifluoromethane (hcfc-22)?
Chlorodifluoromethane (hcfc-22) is not marked as a carcinogen in the TRI classification set. TRI classification flags document inventory listing status; they are not a site-specific exposure or health diagnosis. For health-effect summaries see EPA IRIS and ATSDR toxicological profiles.
Which facilities disclose the most Chlorodifluoromethane (hcfc-22)?
Chemours Louisville Plant in KY reports the largest disclosed release of Chlorodifluoromethane (hcfc-22) in this dataset, at 2.4M lbs. Most reporting facilities for this chemical fall under chemicals. Release data is self-reported annually to the EPA under the TRI program. View the full list of 72 facilities on this page.
What is the CAS number for Chlorodifluoromethane (hcfc-22)?
The CAS (Chemical Abstracts Service) Registry Number for Chlorodifluoromethane (hcfc-22) is 75-45-6. CAS numbers are unique numerical identifiers assigned to every chemical substance described in the open scientific literature. This identifier is used to search scientific databases and regulatory filings.

Health Information

Data comes from the EPA Toxic Release Inventory (TRI) program. Release quantities are self-reported by facilities and may represent estimates. The total shown aggregates reports across all facilities and reporting years.

PlainEnviro presents this data without advocacy framing. The presence of a chemical in the TRI database does not by itself indicate a health risk at current exposure levels. For health-related questions about specific chemical exposures, consult your local health agency or a toxicologist.

Related

Data sourced from the U.S. Environmental Protection Agency (EPA). See our methodology for details. Retrieved and formatted by PlainEnviro

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from the EPA Toxic Release Inventory (TRI). Consult a qualified professional before making decisions based on this data.