Methyl Isobutyl Ketone

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Carcinogen

CAS Number: 108-10-1

Methyl Isobutyl Ketone (CAS 108-10-1) is a chemical tracked by the EPA Toxics Release Inventory (TRI) program under Section 313 of the Emergency Planning and Community Right-to-Know Act. The TRI requires industrial facilities above specified threshold quantities to disclose annual manufacturing, processing, and otherwise-used volumes, along with quantities released to air, water, land, and off-site transfers.

Across the United States, 618 facilities have filed TRI Form R disclosures for Methyl Isobutyl Ketone, with a cumulative reported release volume of 15.6M lbs. The chemical carries a carcinogen classification in the TRI database, based on assessments from EPA, IARC, or the National Toxicology Program. The largest individual disclosure in the current dataset comes from ATI SPECIALTY ALLOYS & COMPONENTS LLC in OR at 1.5M lbs.

TRI volumes are self-reported estimates, not measured stack emissions, and each pound counts equally regardless of chemical toxicity, so total pounds should not be equated with total risk. Inclusion of a chemical or facility in the TRI does not itself establish a health hazard; it documents the public right-to-know record. Consult EPA's IRIS (Integrated Risk Information System) and the Agency for Toxic Substances and Disease Registry for health-effect summaries.

Release Summary

Total Releases
15.6M lbs
Number of Facilities
618
Carcinogen
Yes
Persistent Bioaccumulative Toxicant
No

Which facilities release the most of this chemical?

Facilities with the largest reported releases of Methyl Isobutyl Ketone. Up to 50 shown.

# Facility Release (lbs)
1 Ati Specialty Alloys & Components LLC 1.5M lbs
2 Global Advanced Metals USA 1.0M lbs
3 Pinova,inc. 942.6K lbs
4 Pcs Phosphate Co Inc 941.1K lbs
5 Eastman Chemical Co Tennessee Operations 793.6K lbs
6 Exxonmobil Baton Rouge Refinery (part) 565.0K lbs
7 Nov Quality Tubing 524.9K lbs
8 Fca US Warren Truck Assembly Plant 347.2K lbs
9 Nexeo Solutions LLC 302.6K lbs
10 Carboline Global Inc. 295.3K lbs
11 US Ecology Idaho Inc. 221.2K lbs
12 Ford Motor Company--Kansas City Assembly Plant 212.5K lbs
13 Mueller Co. 191.8K lbs
14 Goodyear Tire & Rubber Co 182.1K lbs
15 Fca US Toledo Assembly Complex 180.0K lbs
16 Prestige Painting Belmont 174.7K lbs
17 Ppg Industries Inc-Oak Creek 164.3K lbs
18 Ford Motor Co Chicago Assembly 150.8K lbs
19 General Motors Wentzville Assembly 148.6K lbs
20 Gm Truck Group Fort Wayne Assembly 142.4K lbs
21 U.S. Naval Air Station North Island 141.6K lbs
22 Cytec Industries Inc 135.7K lbs
23 Toyota Motor Manufacturing Indiana Inc 125.9K lbs
24 Boeing Commercial Airplanes - Everett 122.3K lbs
25 Mbci-Ferdinand Operation 112.6K lbs
26 Nissan N.a. Inc. 109.3K lbs
27 Evonik Corp 90.6K lbs
28 Newmar Corp 88.2K lbs
29 Whirlpool Corp Marion Operations 86.0K lbs
30 Univar Solutions USA 81.6K lbs
31 Ford Motor Co Michigan Assembly Plant 80.9K lbs
32 Altivia Institute Facilities 76.1K lbs
33 Buzzi Unicem Usa-Greencastle Plant 75.1K lbs
34 Bobcat Co (melroe) 74.7K lbs
35 Hutchinson Antivibration Systems Inc 73.1K lbs
36 Meteor Sealing Systems LLC 65.9K lbs
37 Andersen Corp 64.4K lbs
38 Crown Roll Leaf Inc. 62.3K lbs
39 Flexsys America LP Krummrich 61.9K lbs
40 U.s Army Sierra Army Depot 61.7K lbs
41 Solvay USA LLC 61.4K lbs
42 Bobcat-Doosan 61.0K lbs
43 Gm Spring Hill Manufacturing 58.5K lbs
44 Robroy Industries-Texas LLC 56.9K lbs
45 Continental Tire the Americas LLC 56.7K lbs
46 General Motors LLC Bowling Green Assembly Plant 54.6K lbs
47 Thor Wakarusa LLC 54.6K lbs
48 Boeing Commercial Airplane Group - Renton 53.9K lbs
49 Zanini Tennessee Inc. 53.7K lbs
50 Sumiriko Tennessee - Tazewell 52.4K lbs

Frequently Asked Questions

What is Methyl Isobutyl Ketone?
Methyl Isobutyl Ketone (CAS Number: 108-10-1) is a chemical tracked by the EPA Toxic Release Inventory (TRI) program. It is classified as a known or suspected carcinogen. 618 facilities in the United States report releasing this chemical to the EPA.
How much Methyl Isobutyl Ketone is released in the U.S.?
U.S. facilities have reported a total of 15.6M lbs of Methyl Isobutyl Ketone releases to the EPA Toxic Release Inventory across 618 facilities. Release quantities are self-reported estimates. This includes releases to air, water, land, and off-site transfers.
Is Methyl Isobutyl Ketone harmful to health?
Methyl Isobutyl Ketone is classified as a known or suspected carcinogen by the EPA, based on evaluations from IARC, NTP, or EPA itself. Health effects depend on exposure levels, duration, and route. For specific health questions, consult a toxicologist or your local health agency.
Which facilities release the most Methyl Isobutyl Ketone?
The largest reported releasers of Methyl Isobutyl Ketone include facilities across multiple states. Release data is self-reported annually to the EPA under the TRI program. View the full list of 618 facilities on this page.
What is the CAS number for Methyl Isobutyl Ketone?
The CAS (Chemical Abstracts Service) Registry Number for Methyl Isobutyl Ketone is 108-10-1. CAS numbers are unique numerical identifiers assigned to every chemical substance described in the open scientific literature. This identifier is used to search scientific databases and regulatory filings.

Health Information

Carcinogen Classification: This chemical is classified as a known or suspected carcinogen by the EPA under the Toxic Release Inventory program. This classification is based on evaluations by agencies including the International Agency for Research on Cancer (IARC), the National Toxicology Program (NTP), and the EPA itself.

Data comes from the EPA Toxic Release Inventory (TRI) program. Release quantities are self-reported by facilities and may represent estimates. The total shown aggregates reports across all facilities and reporting years.

PlainEnviro presents this data without advocacy framing. The presence of a chemical in the TRI database does not by itself indicate a health risk at current exposure levels. For health-related questions about specific chemical exposures, consult your local health agency or a toxicologist.

Related

Data sourced from the U.S. Environmental Protection Agency (EPA). See our methodology for details. Retrieved and formatted by PlainEnviro Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from the EPA Toxic Release Inventory (TRI). Consult a qualified professional before making decisions based on this data.