1,4-Dioxane

1,4-Dioxane (CAS 123-91-1) is a chemical tracked by the EPA Toxics Release Inventory (TRI) program under Section 313 of the Emergency Planning and Community Right-to-Know Act. The TRI requires industrial facilities above specified threshold quantities to disclose annual manufacturing, processing, and otherwise-used volumes, along with quantities released to air, water, land, and off-site transfers.

Across the United States, 82 facilities have filed TRI Form R disclosures for 1,4-Dioxane, with a cumulative reported release volume of 4.8M lbs. The chemical carries a carcinogen classification in the TRI database, based on assessments from EPA, IARC, or the National Toxicology Program. The largest individual disclosure in the current dataset comes from HUNTSMAN INTERNATIONAL LLC in TX at 2.0M lbs.

TRI volumes are self-reported estimates, not measured stack emissions, and each pound counts equally regardless of chemical toxicity, so total pounds should not be equated with total risk. Inclusion of a chemical or facility in the TRI does not itself establish a health hazard; it documents the public right-to-know record. Consult EPA's IRIS (Integrated Risk Information System) and the Agency for Toxic Substances and Disease Registry for health-effect summaries.