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Dimethyl Sulfate

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Carcinogen

CAS Number: 77-78-1

Dimethyl Sulfate (CAS 77-78-1) is a chemical tracked by the EPA Toxics Release Inventory (TRI) program under Section 313 of the Emergency Planning and Community Right-to-Know Act. The TRI requires industrial facilities above specified threshold quantities to disclose annual manufacturing, processing, and otherwise-used volumes, along with quantities released to air, water, land, and off-site transfers.

Across the United States, 27 facilities have filed TRI Form R disclosures for Dimethyl Sulfate, with a cumulative reported release volume of 11.2K lbs. The chemical carries a carcinogen classification in the TRI database, based on assessments from EPA, IARC, or the National Toxicology Program. The largest individual disclosure in the current dataset comes from STEPAN CO MILLSDALE ROAD in IL at 8.4K lbs.

TRI volumes are self-reported estimates, not measured stack emissions, and each pound counts equally regardless of chemical toxicity, so total pounds should not be equated with total risk. Inclusion of a chemical or facility in the TRI does not itself establish a health hazard; it documents the public right-to-know record. Consult EPA's IRIS (Integrated Risk Information System) and the Agency for Toxic Substances and Disease Registry for health-effect summaries.

Release Summary

Total Releases
11.2K lbs
Number of Facilities
27
Carcinogen
Yes
Persistent Bioaccumulative Toxicant
No

Which facilities release the most of this chemical?

Facilities with the largest reported releases of Dimethyl Sulfate. Up to 50 shown.

# Facility Release (lbs)
1 Stepan Co Millsdale Road 8.4K lbs
2 Stepan Co 1.3K lbs
3 Croda Inc 422 lbs
4 Chemours Belle Plant 395 lbs
5 Evonik Industries 231 lbs
6 Bayer Cropscience LP - Kc 92 lbs
7 Basf Corp - Hannibal Site 60 lbs
8 Chemtrade Refinery Solutions LP 50 lbs
9 Iofina Chemical Inc. 50 lbs
10 3M Chemical Operations' Cordova Facility 45 lbs
11 Eco-Services Operations 44 lbs
12 Lycus Ltd 40 lbs
13 Piedmont Chemical Industries I LLC 26 lbs
14 Veolia Es Technical Solutions LLC Port Arthur Facility 19 lbs
15 Mpm Silicones LLC 15 lbs
16 Pharmacia & Upjohn Co LLC a Subsidiary of Pfizer Inc 12 lbs
17 Clean Harbors el Dorado LLC 1 lbs
18 Ross Incineration Services Inc 0 lbs
19 Heritage Thermal Services 0 lbs
20 Norlite LLC 0 lbs
21 Buckman Laboratories Inc. 0 lbs
22 Abitec Corp Janesville Plant 0 lbs
23 Dow Silicones Corp 0 lbs
24 Chemtall Incorporated; Flocryl LLC 0 lbs
25 Archroma US Inc 0 lbs
26 Weylchem US Inc. 0 lbs
27 Dystar LP 0 lbs

Frequently Asked Questions

What is Dimethyl Sulfate? ▼
Dimethyl Sulfate (CAS Number: 77-78-1) is a chemical tracked by the EPA Toxic Release Inventory (TRI) program. It is classified as a known or suspected carcinogen. 27 facilities in the United States report releasing this chemical to the EPA.
How much Dimethyl Sulfate is released in the U.S.? ▼
U.S. facilities have reported a total of 11.2K lbs of Dimethyl Sulfate releases to the EPA Toxic Release Inventory across 27 facilities. Release quantities are self-reported estimates. This includes releases to air, water, land, and off-site transfers.
Is Dimethyl Sulfate harmful to health? ▼
Dimethyl Sulfate is classified as a known or suspected carcinogen by the EPA, based on evaluations from IARC, NTP, or EPA itself. Health effects depend on exposure levels, duration, and route. For specific health questions, consult a toxicologist or your local health agency.
Which facilities release the most Dimethyl Sulfate? ▼
The largest reported releasers of Dimethyl Sulfate include facilities across multiple states. Release data is self-reported annually to the EPA under the TRI program. View the full list of 27 facilities on this page.
What is the CAS number for Dimethyl Sulfate? ▼
The CAS (Chemical Abstracts Service) Registry Number for Dimethyl Sulfate is 77-78-1. CAS numbers are unique numerical identifiers assigned to every chemical substance described in the open scientific literature. This identifier is used to search scientific databases and regulatory filings.

Related Guides

Understanding TRI Data
How the Toxic Release Inventory works
Biggest Polluters in America
Which facilities release the most toxics
How to Check Environmental Quality
Step-by-step guide to checking your local environment

Health Information

Carcinogen Classification: This chemical is classified as a known or suspected carcinogen by the EPA under the Toxic Release Inventory program. This classification is based on evaluations by agencies including the International Agency for Research on Cancer (IARC), the National Toxicology Program (NTP), and the EPA itself.

Data comes from the EPA Toxic Release Inventory (TRI) program. Release quantities are self-reported by facilities and may represent estimates. The total shown aggregates reports across all facilities and reporting years.

PlainEnviro presents this data without advocacy framing. The presence of a chemical in the TRI database does not by itself indicate a health risk at current exposure levels. For health-related questions about specific chemical exposures, consult your local health agency or a toxicologist.

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Data sourced from the U.S. Environmental Protection Agency (EPA). See our methodology for details. Retrieved and formatted by PlainEnviro Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from the EPA Toxic Release Inventory (TRI). Consult a qualified professional before making decisions based on this data.

Read our methodology - how this data is sourced, computed, and verified.