Isoprene

Isoprene (CAS 78-79-5) is a chemical tracked by the EPA Toxics Release Inventory (TRI) program under Section 313 of the Emergency Planning and Community Right-to-Know Act. The TRI requires industrial facilities above specified threshold quantities to disclose annual manufacturing, processing, and otherwise-used volumes, along with quantities released to air, water, land, and off-site transfers.

Across the United States, 74 facilities have filed TRI Form R disclosures for Isoprene, with a cumulative reported release volume of 819.1K lbs. The chemical carries a carcinogen classification in the TRI database, based on assessments from EPA, IARC, or the National Toxicology Program. The largest individual disclosure in the current dataset comes from GOODYEAR TIRE & RUBBER CO in TX at 353.2K lbs.

TRI volumes are self-reported estimates, not measured stack emissions, and each pound counts equally regardless of chemical toxicity, so total pounds should not be equated with total risk. Inclusion of a chemical or facility in the TRI does not itself establish a health hazard; it documents the public right-to-know record. Consult EPA's IRIS (Integrated Risk Information System) and the Agency for Toxic Substances and Disease Registry for health-effect summaries.